Peer Review Articles

Cost Effectiveness / Pain Management

Skin Closure With Subcuticular Absorbable Staples After Cesarean Section Is Associated With Decreased Analgesic Use
“…[and] would result in a cost savings of approximately $200 per patient even after considering the higher cost of the absorbable staple device.”

Reduced Infection and Inflammation

Surgical Site Infection Rate in 877 Consecutive Cesarean Sections Closed with Absorbable Staples
“...SSI rate of 0.8% in the 877 consecutive cesarean sections [closed with INSORB]...”

A Revolutionary Advance in Skin Closure Compared to Current Methods
“...significantly (p=0.009) lower incidence of infection [in contaminated wounds]...”

Comparison of gross and hystologic tissue response of skin incisions closed by use of absorbable subcuticular staples, cutaneous metal staples and polyglactin 910 suture in pigs
“...[INSORB] induced a less severe inflammatory response [with minimal scaring] in the early stages of healing...”

Obstetrics

Absorbable Subcuticular Staples Compared With Suture for Cesarean Closure: A Randomized Controlled Trial
The subcuticular staple group had significantly shorter skin closure time (2.6 versus 8.5 minutes]... the cost reduction with subcuticular staples [compared to suture] was $172 – $829 per case... One needlestick injury occurred with suture.

Retrospective Review of Wound Complications Following Skin Closure by Either Percutaneous Metal Staples or Absorbable Subcuticular Staples in Patients Undergoing Cesarean Delivery
“…A 7.7% wound complication rate was observed in the absorbable [subcuticular] staple group compared to a 21.3% wound complication rate in the [percutaneous] metal staple group.”

Orthopedics

Comparison of INSORB® Subcuticular Skin Staples and Autosuture™ Signet™ Skin Staples in the Closure of Total Hip Arthroplasty Wounds
“INSORB® subcuticular skin staples act as an adequate method of skin closure in primary hip arthroplasty. They also provide an excellent cosmetic result and high levels of patient satisfaction.”

Knee Arthroplasty Wound Closure With Absorbable Subcuticular Staples - A Retrospective Review Of 104 Consecutive Procedures
“Based on the results of our study, we conclude that absorbable subcuticular staples offer a secure, efficient, and effective method of skin closure. Our findings suggest that absorbable subcuticular staples are a preferred skin closure modality in knee arthroplasty due to improved wound healing with a remarkable lack of inflammation, time savings in surgery and in clinic, cosmetic advantages, and improved patient satisfaction compared to our experience with subcuticular suture and percutaneous metal staples.”

A randomized prospective study of total hip wound closure with resorbable subcuticular staples
“... [INSORB] can provide comparable wound closure to stainless steel staples following total hip replacement and may do so with less local discomfort or erythematous reaction.”

Transplant

Renal transplant incision closures using new absorbable subcuticular staple device
“... [INSORB Staples] are secure and effective and are preferable to metal staple closures even in renal transplant recipients receiving steroids and sirolimus.”

Plastic Surgery

Donor-site closure using absorbable dermal staple for deep inferior epigastric artery perforator flaps: its efficacy and cosmetic outcomes
“Absorbable dermal stapling reduced operative time, compared to that of traditional suturing. In addition, scar quality from absorbable dermal staples was superior to that resulting from traditional sutures.”

Placement of Absorbable Dermal Staples in Mammaplasty and Abdominoplasty: A 12-Month Prospective Study of 60 Patients
“Closure with absorbable staples was approximately 7-fold faster than closure with absorbable sutures for all [mammaplasty and abdominoplasty] surgical procedures…Absorbable staples enable faster closure of a surgical incision without compromising scar quality or patient comfort.”

The Dermal Stapler Device: A faster more cost-effective method for Incisional closures as compared to Standard Dermal Surtures
“... [INSORB] is 4 times faster than suture closure, saving...$220/closure.”

Colorectal Surgery

Reduction Of Surgical Site Infections In Colorectal Surgery By The Combined Use Of Absorbable Subcuticular Staple Closure And Silver Nylon Dressings: A Retrospective Review Comparing To Percutaneous Metal Staples With Gauze Dressings
“…absorbable staples and silver dressing demonstrated a significant decrease in SSI (9% vs 0%) and patients expressed high satisfaction with wound comfort and appearance.”

Metal Skin Staples

Retrospective Review of Wound Complications Following Skin Closure by Either Percutaneous Metal Staples or Absorbable Subcuticular Staples in Patients Undergoing Cesarean Delivery
“…A 7.7% wound complication rate was observed in the absorbable [subcuticular] staple group compared to a 21.3% wound complication rate in the [percutaneous] metal staple group.”

[Metal] staples vs subcuticular sutures for skin closure at cesarean delivery: a metaanalysis of randomized controlled trials
"... Both wound separation and composite wound complication rates were higher with [metal] staples."

[Metal] Staples Compared With Subcuticular Suture for Skin Closure After Cesarean Delivery
"... [Metal] staple closure is faster to perform [than suture] but associated with a higher risk of wound complications."

Risk of Wound Infection Is Greater After Skin Closure with [Metal] Staples Than with Sutures in Orthopaedic Surgery
"... On the basis of evidence with numerous methodological limitations, patients having orthopaedic surgery are at greater risk for wound infection after skin closure with [metal] staples than they are after skin closure with sutures."

A Randomized Controlled Trial Of Wound Complication Rates Of Subcuticular Suture Vs [Metal] Staples For Skin Closure At Cesarean Delivery
"... Use of [metal] staples for cesarean delivery closure is associated with an increased risk of wound complications and post-operative physician visits."

Surgical [Metal] Staples Compared With Subcuticular Suture for Skin Closure After Cesarean Delivery: A Randomized Controlled Trial
"Percutaneous Metal] Staples closure compared with [subcuticular] suture is associated with significantly increased composite wound morbidity [14X] after cesarean delivery."